Growth Hormone Secretion Pathways

• Sermorelin (GRF 1–29) is a synthetic peptide analog of growth-hormone–releasing hormone (GHRH) that has been studied in pre-clinical and cellular models for its ability to stimulate pituitary GH release and upregulate IGF-1–related pathways in endocrine research.

Skeletal-Muscle Growth and Recovery

• Experimental studies demonstrate that Sermorelin-induced GH signaling supports myoblast proliferation, protein synthesis, and recovery mechanisms in muscle-tissue culture and animal models, providing a platform for anabolic and regenerative research.

Metabolic and Lipid Oxidation Studies

• In non-clinical systems, GH-axis modulation by Sermorelin has been linked to enhanced fat oxidation, improved mitochondrial efficiency, and altered nutrient-partitioning patterns, making it a valuable compound for studying metabolic regulation.

Sleep and Circadian Rhythm Research

• Pre-clinical literature suggests that Sermorelin may influence pulsatile GH secretion during slow-wave sleep phases, enabling investigations into neuroendocrine feedback loops and circadian hormone rhythms.

Dermal and Collagen-Synthesis Models

• In fibroblast and tissue-culture systems, GH and IGF-1 signaling stimulated by GHRH analogs such as Sermorelin has been associated with collagen synthesis and extracellular-matrix remodeling, supporting studies in skin physiology and repair.

Immune Modulation Research

• GH-axis stimulation has been explored for its potential to influence cytokine expression and immune-cell function, allowing use of Sermorelin in immune-regulation and recovery-assay models.

Cognitive and Neuroendocrine Studies

• Non-clinical investigations link GH signaling to neuroplasticity and neurotrophic-factor modulation, making Sermorelin a relevant research compound for studying memory, focus, and cognitive resilience.

STORAGE DETAILS

Lyophilized Sermorelin peptide is stable at room temperature for 90 days; however, it should NOT be stored below freezing for any extended period. After reconstitution, refrigerate at ≤36°F.

Product Specifications

• Appearance: Solid, white powder in 3mL glass ampule

• Chemical Formula: C149H246N44O42S

• PubChem CID: 16133819

• CAS Number: 86168-78-7

• Molecular Weight: 3357.96 g/mol

• Synonyms: GRF 1-29, GHRH 1-29, 86168-78-7

• Storage: Store at ≤6°C, sealed, away from heat, light, and moisture.

• Concentration: ≥98%

  Research Use Only (RUO). Not for human or animal use. Not for diagnostic, therapeutic, or clinical applications. No claims are made regarding growth hormone stimulation, fat loss, or anti-aging effects in humans. End-user assumes responsibility for determining suitability for specific research protocols.