Cognitive and Neurocognitive-Function Research

• Semax is a synthetic peptide derivative of adrenocorticotropic hormone (ACTH 4–10) studied in pre-clinical and cellular systems for its ability to influence learning, memory consolidation, and neurocognitive performance via modulation of neurotransmitter and neurotrophic signaling pathways.

Neuroprotection and Oxidative-Stress Models

• Laboratory studies show Semax can enhance neuronal resistance to oxidative stress and excitotoxic damage, supporting its use in neuroprotection, mitochondrial stability, and antioxidant-defense research.

Mood and Stress-Response Regulation Studies

• In animal models, Semax has been observed to modulate monoaminergic neurotransmission, enabling investigations into antidepressant, anxiolytic, and stress-resilience mechanisms at the neurochemical level.

Neurotrophic-Factor and BDNF Expression Research

• Experimental findings indicate that Semax upregulates brain-derived neurotrophic factor (BDNF) and related growth-pathway proteins, providing a foundation for research on neural regeneration, synaptic plasticity, and cognitive recovery.

Attention and Focus Mechanisms

• In pre-clinical research, Semax has been used to study attention control, executive function, and dopaminergic signaling, making it a useful compound for models of neurofocus and cognitive-clarity processes.

Neuroregeneration and Ischemic-Injury Models

• Semax has demonstrated potential neurorestorative effects in animal stroke and traumatic brain injury models, facilitating exploration of ischemic tolerance and neurovascular recovery.

Immune and Inflammatory Modulation Studies

• Laboratory data suggest that Semax may modulate cytokine expression and neuroimmune crosstalk, supporting research on inflammation-related neural disorders and systemic immune regulation.

STORAGE DETAILS

Lyophilized SEMAX is stable at room temperature for 90 days; however, it should NOT be stored below freezing for extended periods. After reconstitution, refrigerate at ≤36°F.

Product Specifications

• Application: Research peptide with potential in cognitive enhancement

• Appearance: Solid, white powder in 3mL glass ampule

• Chemical Formula: C37H51N9O10S

• PubChem CID: 9811102

• CAS Number: 80714-61-0

• Molecular Weight: 813.94 g/mol

• Synonyms: Semax, Phenylacetyl-L-prolylglycyl-L-proline ethyl ester

• Storage: Store at ≤6°C, sealed, away from heat, light, and moisture.

• Concentration: ≥98%

  Research Use Only (RUO). Not for human or animal use. Not for diagnostic, therapeutic, or clinical applications. No claims are made regarding cognitive enhancement, mood regulation, or neuro-protection in humans. End-user assumes responsibility for determining suitability for specific research protocols.