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Mitochondrial Function and Cellular-Energy Research

• Nicotinamide Adenine Dinucleotide (NAD⁺) is a coenzyme central to oxidative phosphorylation and redox metabolism. It is studied in cellular and pre-clinical models for its ability to drive mitochondrial ATP production and regulate energy-transfer processes within cells.

Neuroprotection and Cognitive-Function Studies

• In in-vitro systems, NAD⁺ has been shown to modulate neuronal survival, synaptic integrity, and neurotransmitter balance, supporting its use in neurodegeneration and cognitive-performance research.

DNA-Repair and Genomic-Stability Models

• Experimental findings demonstrate that NAD⁺ serves as a substrate for PARP and SIRT-family enzymes involved in DNA repair, genomic protection, and chromatin remodeling, allowing its use in studies of oxidative damage and cellular senescence.

Longevity and Sirtuin-Activation Research

• Pre-clinical data indicate NAD⁺ regulates sirtuin-dependent pathways that influence cellular metabolism, autophagy, and lifespan, making it a key molecule for studying anti-aging and longevity-related mechanisms.

Metabolic and Energy-Utilization Studies

• In animal research, NAD⁺ levels correlate with improved lipid oxidation and glucose utilization, supporting its use in metabolic-efficiency, mitochondrial-function, and nutrient-partitioning models.

Inflammation and Oxidative-Stress Studies

• NAD⁺ is involved in redox signaling and the regulation of pro-inflammatory cytokines. Experimental models have used it to examine mechanisms of oxidative-stress resistance and inflammatory homeostasis.

Muscle-Recovery and Exercise-Performance Research

• Laboratory studies indicate NAD⁺ influences mitochondrial biogenesis and muscle endurance, enabling its use in recovery, energy output, and fatigue-resistance research.

Detoxification and Cellular-Repair Mechanisms

• In pre-clinical systems, NAD⁺ plays a role in hepatic detoxification and the neutralization of reactive oxygen species (ROS), providing a foundation for cellular-restoration and metabolic-cleansing studies.

Cardiovascular and Endothelial Function Studies

• NAD⁺ and its redox cycle are integral to nitric-oxide synthesis and endothelial-cell signaling, making it suitable for examining vascular reactivity, microcirculation, and cardiac-metabolism pathways.

Neurotransmitter and Mood-Regulation Research

• Experimental evidence links NAD⁺-dependent enzymes to neurotransmitter synthesis and neuronal energy metabolism, supporting its use in stress-response and neurochemical-balance research.

STORAGE DETAILS

Lyophilized Nicotinamide Adenine Dinucleotide (NAD+)  is stable at room temperature for 90 days; however, it should NOT be stored below freezing for any extended period. After reconstitution, refrigerate at ≤36°F.

Product Specifications

• Application: Research peptide coenzyme involved in various metabolic processes

• Appearance: Solid, white powder in 5ml glass ampule

• Chemical Formula: C21H27N7O14P2

• PubChem CID: 5893

• CAS Number: 53-84-9

• Molecular Weight: ~663.43 g/mol

• Synonyms: Nicotinamide adenine dinucleotide, Coenzyme I, β-NAD, NADH

• Storage: Store at -10°C, sealed, away from heat, light, and moisture.

• Concentration: ≥99%

  Research Use Only (RUO). Not for human or animal use. Not for diagnostic, therapeutic, or clinical applications. No claims are made regarding energy enhancement, anti-aging, or neuro-protection in humans. End-user assumes responsibility for determining suitability for specific research protocols.