Mitochondrial Bioenergetics and Cellular-Energy Research

• MOTS-C (Mitochondrial-Derived Peptide, 16 amino acids) has been studied in pre-clinical systems for its ability to regulate mitochondrial gene expression, enhance oxidative metabolism, and promote energy efficiency through AMPK activation and downstream metabolic pathways.

Lipid-Oxidation and Glucose-Regulation Models

• In animal and cell-culture studies, MOTS-C has been shown to increase fatty-acid oxidation and improve glucose utilization, providing a framework for examining metabolic flexibility and mitochondrial adaptation.

Insulin-Sensitivity and Glucose-Homeostasis Research

• Experimental data suggest that MOTS-C enhances insulin sensitivity by modulating cellular stress responses and metabolic transcription factors such as NRF2 and PGC-1α, making it a useful compound for studying metabolic-syndrome mechanisms.

Aging and Longevity Pathway Studies

• Pre-clinical research indicates MOTS-C may influence AMPK and sirtuin signaling, enabling exploration of mitochondrial quality control, cellular senescence, and longevity pathways in aging-model organisms.

Physical-Endurance and Performance Models

• In rodent studies, MOTS-C has been associated with improved exercise capacity and reduced fatigue through enhanced ATP turnover and mitochondrial density, allowing investigation into endurance and recovery biology.

Cognitive and Neuroenergetic Research

• Laboratory findings suggest MOTS-C can cross the blood–brain barrier and may influence neuronal energy metabolism, supporting research into mitochondrial regulation of cognitive function and memory formation.

Cardiovascular and Vascular-Function Studies

• Pre-clinical literature reports improved endothelial function and reduced oxidative stress in cardiac tissue following MOTS-C administration, making it relevant for studies of mitochondrial cardioprotection and vascular health.

STORAGE DETAILS

Lyophilized MOTS-c peptide is stable at room temperature for 90 days; however, it should NOT be stored below freezing for any extended period. After reconstitution, refrigerate at ≤36°F.

Product Specifications

• Appearance: Solid, white powder in 3mL glass ampule

• Chemical Formula: C39H50N14O9

• PubChem CID: (Specify if available)

• CAS Number: 1627583-67-3

• Molecular Weight: 796.91 g/mol

• Synonyms: MOTS-c Peptide, 1627583-67-3

• Storage: Store at ≤6°C, sealed, away from heat, light, and moisture.

• Concentration: ≥98%

  Research Use Only (RUO). Not for human or animal use. Not for diagnostic, therapeutic, or clinical applications. No claims are made regarding fat loss, energy enhancement, or anti-aging benefits in humans. End-user assumes responsibility for determining suitability for specific research protocols.