LL-37 Complex (5mg)
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Existing research has found the following:
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Supports Antimicrobial Peptide Research – Studied for its broad-spectrum activity against bacterial, viral, and fungal pathogens in experimental models.
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Explores Immune Modulation Pathways – Investigated for its role in enhancing innate immune response and coordinating host defense mechanisms.
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Evaluates Wound Healing & Tissue Repair – Examined for promoting epithelial regeneration and accelerating skin and soft tissue recovery.
Description
Antimicrobial and Host-Defense Studies
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LL-37 Complex is a research-grade blend containing the human cathelicidin peptide LL-37 and complementary immune-modulatory components. In pre-clinical and cellular models, LL-37 and its synergistic cofactors have been shown to display broad-spectrum antimicrobial activity against bacteria, fungi, and enveloped viruses.
Immune-System Modulation
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In non-clinical experiments, LL-37 and related peptides have been observed to regulate cytokine production, enhance macrophage activation, and balance immune-cell signaling, allowing study of innate and adaptive immune-response pathways.
Wound-Healing and Tissue-Regeneration Models
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Experimental data demonstrate that LL-37 accelerates re-epithelialization, angiogenesis, and fibroblast migration, supporting its use in research on tissue-repair and wound-healing mechanisms.
Inflammatory and Autoimmune Research
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Pre-clinical findings indicate that LL-37 can modulate inflammatory cascades by influencing NF-κB and Toll-like receptor pathways, enabling exploration of chronic-inflammation and immune-dysregulation models.
Gastrointestinal and Microbiome Studies
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In in-vitro assays, LL-37 and its analogs have been studied for their effects on epithelial-barrier integrity, mucosal immunity, and microbial diversity—providing a tool for gastrointestinal and microbiota research.
Respiratory and Pulmonary Models
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Non-clinical literature supports the use of LL-37 in examining immune and antimicrobial mechanisms within lung tissue, aiding studies of airway defense, infection recovery, and mucosal resilience.
Autoimmunity and Immune-Tolerance Mechanisms
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LL-37 and its complexed forms have been used to evaluate immune recognition and tolerance signaling in autoimmune-disease models such as rheumatoid arthritis and lupus, helping elucidate peptide-mediated immune-regulation dynamics.
STORAGE DETAILS
Lyophilized LL-37 Complex peptide is stable at room temperature for 90 days; however, it should NOT be stored below freezing for any extended period. After reconstitution, refrigerate at ≤36°F.
Product Specifications
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Appearance: Solid, white powder in 3mL glass ampule
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Chemical Formula: C177H293N51O43
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CAS Number: 219685-50-4
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Molecular Weight: 4493.23 g/mol
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Synonyms: LL-37, CAP-18, FALL-39, 219685-50-4
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Storage: Store at ≤6°C, sealed, away from heat, light, and moisture.
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Concentration: ≥98%
Research Use Only (RUO). Not for human or animal use. Not for diagnostic, therapeutic, or clinical applications. No claims are made regarding antimicrobial, immune, or wound-healing benefits in humans. End-user assumes responsibility for determining suitability for specific research protocols.






