Anti-Inflammatory and Cytokine-Modulation Studies

• KPV, a naturally occurring tripeptide fragment of α-melanocyte-stimulating hormone (α-MSH), has been studied in pre-clinical and cellular systems for its strong anti-inflammatory activity, particularly through inhibition of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Gastrointestinal-Barrier and Gut-Healing Research

• In animal and cell-culture models, KPV has been observed to protect intestinal epithelium, modulate immune signaling, and support epithelial regeneration, making it a useful compound for studying inflammatory bowel conditions and gut-mucosal integrity.

Dermal and Wound-Healing Pathway Studies

• Pre-clinical literature reports accelerated keratinocyte migration, collagen remodeling, and reduced local inflammation in KPV-treated wound models, supporting its use in tissue-repair and dermatologic-healing research.

Immune-Regulation and Autoimmune Models

• Experimental findings suggest that KPV can down-regulate excessive immune responses by modulating melanocortin receptors, providing insight into autoimmune-response control and immune-homeostasis mechanisms.

Digestive and Intestinal-Comfort Models

• Laboratory research indicates that KPV may help maintain gastrointestinal permeability and reduce localized gut irritation, offering a basis for studying digestive comfort and microbiome-stability pathways.

Tissue-Regeneration and Recovery Research

• KPV has been evaluated in non-clinical systems for its ability to promote fibroblast proliferation and angiogenesis, enabling examination of peptide-mediated tissue-repair and regenerative-signaling cascades.

Antimicrobial and Host-Defense Studies

• Pre-clinical data show that KPV exhibits antimicrobial activity against several bacterial species while preserving beneficial microflora, allowing exploration of innate-defense and infection-prevention mechanisms.

STORAGE DETAILS

Lyophilized KPV peptide is stable at room temperature for 90 days; however, it should NOT be stored below freezing for any extended period. After reconstitution, refrigerate at ≤36°F.

Product Specifications

• Appearance: Solid, white powder in 3mL glass ampule

• Chemical Formula: C16H26N4O4

• PubChem CID: (Specify if available)

• CAS Number: 67727-97-3

• Molecular Weight: 338.41 g/mol

• Synonyms: KPV Tripeptide, α-MSH(11-13), 67727-97-3

• Storage: Store at ≤6°C, sealed, away from heat, light, and moisture.

• Concentration: ≥98%

  Research Use Only (RUO). Not for human or animal use. Not for diagnostic, therapeutic, or clinical applications. No claims are made regarding inflammation reduction, gut healing, or antimicrobial effects in humans. End-user assumes responsibility for determining suitability for specific research protocols.