Gonadotropin and Reproductive Axis Regulation

• Kisspeptin, a peptide encoded by the KISS1 gene, has been studied in pre-clinical and cell-based systems for its essential role in activating gonadotropin-releasing hormone (GnRH) neurons, forming the foundation for research on reproductive endocrinology and hypothalamic signaling.

Fertility and Reproductive Hormone Studies

• In animal models, Kisspeptin administration has been shown to stimulate luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion, supporting investigations into the hypothalamic-pituitary-gonadal (HPG) axis and fertility-regulation pathways.

Sex-Hormone Regulation Mechanisms

• Experimental findings indicate that Kisspeptin influences downstream production of testosterone and estrogen through modulation of GnRH pulse frequency, providing a model for studying hormonal homeostasis and reproductive physiology.

Neuroendocrine and Behavioral Research

• Kisspeptin has been used in non-clinical studies to explore central mechanisms involved in sexual motivation, affect regulation, and emotional-cognitive integration, enabling further understanding of reproductive neurobiology.

Puberty-Onset and Developmental Models

• In pre-clinical systems, Kisspeptin signaling is critical for initiating puberty through hypothalamic activation and gonadotropin release, making it a useful compound for studying developmental endocrinology and maturation timing.

Mood and Cognitive-Function Research

• Laboratory studies indicate that Kisspeptin interacts with limbic brain regions, offering a framework for examining its role in mood regulation, cognition, and neural signaling.

Metabolic and Energy-Homeostasis Studies

• In metabolic-research models, Kisspeptin has been linked to appetite regulation and energy-expenditure pathways, providing insight into the intersection of reproduction and metabolic control.

STORAGE DETAILS

Lyophilized Kisspeptin peptide is stable at room temperature for 90 days; however, it should NOT be stored below freezing for any extended period. After reconstitution, refrigerate at ≤36°F.

Product Specifications

• Appearance: Solid, white powder in 3mL glass ampule

• Chemical Formula: C63H83N17O14

• PubChem CID: (Specify if available)

• CAS Number: 374822-39-2

• Molecular Weight: 1302.46 g/mol

• Synonyms: Metastin, Kisspeptin-10, Kiss1, 374822-39-2

• Storage: Store at ≤6°C, sealed, away from heat, light, and moisture.

• Concentration: ≥98%

  Research Use Only (RUO). Not for human or animal use. Not for diagnostic, therapeutic, or clinical applications. No claims are made regarding fertility, libido, or hormonal enhancement in humans. End-user assumes responsibility for determining suitability for specific research protocols.