Reproductive-Endocrine Axis Research

• Gonadorelin (synthetic Gonadotropin-Releasing Hormone, or GnRH) is used in cellular and pre-clinical studies to model hypothalamic–pituitary–gonadal (HPG) axis signaling. It stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland in experimental systems.

Testosterone and Estrogen Regulation Studies

• In animal models, Gonadorelin is used to investigate LH/FSH-mediated steroidogenesis, supporting research into the regulation of testosterone and estrogen synthesis and the downstream effects on reproductive tissues.

Fertility and Ovulatory Function Research

• Laboratory data show Gonadorelin can induce LH surges that mimic the ovulatory signal, making it a valuable tool in research related to ovulation, spermatogenesis, and gonadal development.

Post-Cycle and Hormone-Suppression Studies

• Gonadorelin is used in endocrine-model research to study pituitary responsiveness and the restoration of HPG function following exogenous hormone exposure, providing insight into feedback-loop recovery mechanisms.

Hypogonadism and Hormonal-Imbalance Research

• Pre-clinical studies explore Gonadorelin’s ability to normalize gonadotropin levels, enabling mechanistic studies of hypogonadism, delayed puberty, and other hormone-deficiency models.

Testicular-Function and Leydig-Cell Models

• In male endocrine research, Gonadorelin is utilized to stimulate LH release and testicular Leydig-cell activation, helping to map testosterone synthesis pathways and gonadal resilience mechanisms.

Female Reproductive and Ovulatory Models

• Gonadorelin serves as an experimental control for investigating follicular maturation, ovulation, and corpus luteum function, allowing insight into female reproductive hormone dynamics.

Neuroendocrine and Feedback Pathway Studies

• Research shows that Gonadorelin plays a role in exploring hypothalamic feedback, GnRH receptor sensitivity, and neuroendocrine rhythm regulation in circadian and reproductive studies.

STORAGE DETAILS

Lyophilized Gonadorelin peptide is stable at room temperature for 90 days; however, it should NOT be stored below freezing for any extended period. After reconstitution, refrigerate at ≤36°F.

Product Specifications

• Appearance: Solid, white powder in 3mL glass ampule

• Chemical Formula: C55H75N17O13

• PubChem CID: 638793

• CAS Number: 33515092

• Molecular Weight: 1182.311 g/mol

• Synonyms: Luteinizing hormone-releasing hormone, Gonadoliberin, Dirigestran, Factrel, Fertagyl, Hypocrine, Gonadorelin hydrochloride

• Storage: Store at ≤6°C, sealed, away from heat, light, and moisture.

• Concentration: ≥98%

  Research Use Only (RUO). Not for human or animal use. Not for diagnostic, therapeutic, or clinical applications. No claims are made regarding testosterone enhancement, fertility improvement, or hormonal therapy in humans. End-user assumes responsibility for determining suitability for specific research protocols.