Antioxidant and Redox-Balance Research

• Curcumin, a polyphenolic compound derived from Curcuma longa (turmeric), has been widely studied in cellularand pre-clinical models for its potent free-radical scavenging properties and ability to modulate oxidative-stress–related pathways such as NRF2 and HO-1 activation.

Anti-Inflammatory Pathway Studies

• In in-vitro and animal systems, Curcumin has been observed to regulate NF-κB, COX-2, and cytokine expression, supporting its use in research involving inflammatory signaling, immune balance, and tissue homeostasis.

Neuroprotection and Cognitive Function Research

• Pre-clinical findings suggest that Curcumin may influence neuronal health by modulating amyloid aggregation, neurotrophic factors, and mitochondrial function, providing a foundation for studies on neuroprotection and memory processes.

Joint, Muscle, and Mobility Models

• Experimental data demonstrate Curcumin’s ability to regulate inflammatory mediators in connective tissue, aiding investigations into muscle recovery, joint resilience, and cartilage health.

Cardiovascular and Circulatory Studies

• In non-clinical models, Curcumin has been linked to endothelial nitric-oxide regulation, lipid balance, and reduction of oxidative plaque formation, allowing exploration of vascular and cardiac-function pathways.

Immunomodulation and Host-Defense Research

• Laboratory studies have shown Curcumin to influence immune signaling via macrophage activation and cytokine modulation, making it a valuable compound for immune-response and host-defense research.

Liver Detoxification and Xenobiotic-Metabolism Studies

• Curcumin has been examined in hepatocyte models for its ability to induce phase II detoxification enzymes and glutathione-related pathways, providing a tool for liver-function and toxin-clearance research.

Oncology and Cell-Health Models

• Pre-clinical studies indicate that Curcumin can modulate cell-cycle checkpoints, apoptosis signaling, and tumor-suppressor gene expression, supporting its use in early-stage cancer biology and chemoprevention research.

Gastrointestinal and Microbiome Studies

• Curcumin has been investigated for its impact on gut-barrier integrity, microbial diversity, and inflammation within the intestinal mucosa, aiding research on digestion, microbiota balance, and gastrointestinal resilience.

STORAGE DETAILS

Lyophilized Curcumin is stable at room temperature for 90 days; however, it should NOT be stored below freezing for any extended period of time. After reconstituting, Curcumin should be refrigerated at temperatures not to exceed 36°F.

Product Specifications

• Appearance: Solid, yellow-orange powder in 3mL glass ampule

• Chemical Formula: C21H20O6

• PubChem CID: 969516

• CAS Number: 458-37-7

• Molecular Weight: 368.39 g/mol

• Synonyms: Diferuloylmethane, Curcumin, 458-37-7

• Storage: Store at ≤6°C, sealed, away from heat, light, and moisture.

• Concentration: ≥98%

  Research Use Only (RUO). Not for human or animal use. Not for diagnostic, therapeutic, or clinical applications. No claims are made regarding antioxidant, anti-inflammatory, or disease-prevention benefits in humans. End-user assumes responsibility for determining suitability for specific research protocols.